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The 24 individuals with obesity were taking a maintenance dose of GLP-1RA medication for weight loss ( N = 14, GLP-1RA group) for at least 30 days, or not taking any medication for weight loss ( N = 10, control group)

To examine the transportation of GHSR and GLP-1R within the vagal afferents, we studied bindings of 125 I-ghrelin and 125 I-GLP-1 in the vagal segments