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Here is how the semaglutide titration typically unfolds after switching: Source: FDA Prescribing Information, Wegovy 2025 Your provider may adjust this schedule based on your history for example, some clinicians allow patients with excellent prior GLP-1 tolerance to move through the early doses more quickly

Injection site related discomfort

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If you take insulin or other diabetes medications, your provider may need to adjust your doses to prevent dangerously low blood sugar