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Blood was collected at 0.25, 0.5, 1, 2, 4, 8, 24 and 48 h for subcutaneous and oral gavage groups

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To begin to investigate functional changes in lipid metabolism, we first tested if loss of ACLY and ACSS2 resulted in dependence on exogenous lipids

Metabolic benefitslike improved insulin sensitivity, blood pressure, and triglyceride levelswere seen within 68 weeks