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Structural changes in this active center are closely linked to the enzymes catalytic activity, which determines its ability to oxidize tyrosine 15

Hodgson JM, Watts GF, Playford DA, et al

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Its ability to neutralise free radicals has led to it often being referred to as the master antioxidant

As epigenetic modifiers, STLs can modulate the p53 signaling pathway, suppress oncogenic signaling pathways, reduce the activation of major hepatocarcinogenesis-related oncogenes, and inhibit the epithelial-mesenchymal transition [110,111,112]