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Cross-compound receptor-occupancy percentages are deliberately not compared here: occupancy (pRO) is a modeled inference, not a measurement, and Willard 2020 cautions that "calculating pRO values has caveats." Binding affinity is the measured quantity

Cardiovascular benefits of GLP-1-based therapies in patients with diabetes mellitus type 2: Effects on endothelial and vascular dysfunction beyond glycemic control

This is why we've found it to be a sweet spot for most research applications

GLP-1 medications most commonly cause gastrointestinal symptoms (including nausea, constipation, and diarrhea)

This is the mechanism behind the prolonged fullness that GLP-1 drug users describe