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The insulin resistance in PCOS might also occur independently of body weight, due to inherited post-receptor defects in insulin signalling that affects metabolism and mitotic pathways, not only in classic insulin target tissues, such as skeletal muscle, liver, and adipose tissue, but also in the non-classical target tissues, such as pituitary and ovary [12, 16]

These benefits include cardiovascular risk reduction, heart failure hospitalization rate reduction, kidney disease progression risk reduction, and weight loss

In a class action, courts typically determine damages (monetary awards) on a collective basis

Our goal at Dr

doi: 10.1038/nn.4540, 150 van BloemendaalL.RgI