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2, indicated as X) and form conjugates with GSH either spontaneously or enzymatically in reactions catalyzed by GSH-S-transferase (Meister, 1988)

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For further information, refer to the New Zealand Formulary: Discuss potential adverse effects before initiating treatment Adverse effects of SGLT-2 inhibitors such as empagliflozin include: 11 Polyuria consider reducing diuretics before initiating treatment Genitourinary infections, e.g

For comparison, metformin one of the most common diabetes drugs in the world has bioavailability of 40-60%

The bloodbrain barrier