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A recent letter in Annals of Internal Medicine led by my colleagues Tim Kambi and Jan Karregat highlights this issue clearly: Similarly, work by my colleague Carla Prado, PhD, RD, FCAHS underscores that reductions in lean mass during GLP-1induced weight loss are common

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Retatrutide is a medication that activates three metabolic pathways: GLP-1 , which helps regulate appetite and blood sugar

While traditional weight loss methods such as dieting and exercise have been the go-to approach, emerging pharmaceutical options like tesofensine are gaining attention for their potential efficacy