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Biological & Pharmaceutical Bulletin 31 (9): 1673-1679

These medications slow gastric emptying to help control blood glucose and appetite, but this can lead to increased gas production and digestive discomfort

Your brain's appetite centers receive signals faster than your scale reflects weight loss, which is why many people report feeling fuller at meals before the numbers change

For continuation, NICE requires at least an 11 mmol/mol reduction in HbA1c and 3% body weight loss at 6 months