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Research suggests that individuals with this disease have compromised levels of glutathione in their brains

Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL

The neuronal lineage commitment of NPCs, their exit from the cell cycle and further neuronal maturation is initiated by TFs of the basic helix-loop-helix (bHLH) family: Ngn2, NeuroD1 and NeuroD2 (Pleasure et al., 2000

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StatPearls [Internet] 94