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these act as direct free radical scavengers and also support enzymatic systems Glutathione Uric acid Coenzyme Q10 (ubiquinone) Lipoic acid Melanin (often overlooked but very relevant in skin) While endogenous antioxidant systems provide continuous intrinsic protection, they are insufficient to counteract the cumulative oxidative burden imposed by ultraviolet radiation, pollution, lifestyle factors, and aesthetic procedures

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Pseudomonas aeruginosa AES-1 exhibits increased virulence gene expression during chronic infection of cystic fibrosis lung

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This is because skin cells take time to turn over and regenerate