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Mol Metab 2015, 4: 718731

"For retatrutide, the findings from TRIUMPH-4 are encouraging, and with seven additional phase 3 readouts expected in 2026, we believe retatrutide could become an important option for patients with significant weight loss needs and certain complications, including knee osteoarthritis," a Lilly spokesperson said in a statement to Fox News Digital

Understanding Semaglutide Semaglutide is a medication that mimics the action of the GLP-1 hormone

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The mechanisms involved changes in short-chain fatty acid production, particularly acetic acid, which has been shown to promote circulating levels of GLP-1 and PYY (peptide YY, another satiety hormone)