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J Clin Med 10(8):1798

Furthermore, GLS has been identified as the first rate-limiting enzyme in glutamine metabolism, which has emerged as a potential therapeutic target for tumours

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Apoptosis due to inflammation, ERS, and oxidative stress has long been thought to be the main cause of cell dysfunction

Peer review Peer review information Nature Reviews Rheumatology thanks Melek Kechida, Durga Misra and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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