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Updated on May 12, 2025.

Deficiency may slow or prevent growth in children (5)

Because while GLP-1 medications can help you lose weight, they can also lead to a loss of lean muscle without the right plan in place

The current model is that when the DTC presenting LAG-2 and APX-1 interacts with GLP-1 expressed in germ cells, ligand dependent cleavage of the receptor generates the GLP-1 intracellular domain, GLP-1(ICD), which translocates to the nucleus and associates with the sequence specific DNA binding protein LAG-1 to activate primary target gene transcription