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and 27% of patients were lost or unsuitable for evaluation , meaning the headline denominator is 49, not 67

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3.3 Potential biomarkers associated with PCa prognosis A total of 48 articles ( Table 4 , Supplementary Table 4 ) (50, 58, 59, 61, 63, 64, 70, 71, 73, 74, 80, 86, 88, 109, 110, 113, 124155) evaluating 147 potential biomarkers related to PCa prognosis were identified across 11 countries/territories

FIGURE 8 3.5 Establishment and validation of Deg-AZM PBPK models in rats The parameters collected from preclinical studies were used to establish PBPK models of Deg-AZM (listed in Table 7), followed by validation using PK data of rats

After reaching target organs through blood circulation, the iron bound TF then binds up to the transferrin receptor 1 (TFR1) and is internalized under the clathrin-dependent endocytosis