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Patients should contact their GP or healthcare provider if they experience no bowel movement for more than seven days despite using laxatives, as this may indicate severe constipation or faecal impaction requiring medical intervention

Liver disease caused by fatty deposits that are not related to drinking alcohol is increasingly seen as a cause of this condition

Hormonal Imbalances Thyroid hormone imbalances, such as hypothyroidism , reduce methylation efficiency by affecting metabolic processes and enzyme activities

Patients can expect substantial weight reduction, often 10-20% of total body weight

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