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Las investigaciones demuestran que tambin desempea un papel clave en la mejora de la resistencia del organismo a la insulina

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The importance of brain-derived GLP-1, the direct vs indirect actions of GLP-1 and GLP-1-induced control of neural activity is extensively discussed since many organs and cellular targets of GLP-1 action do not exhibit detectable levels of GLP-1R [20,21,22,23]

For instance, chronic constipation may lead to haemorrhoids or anal fissures, whilst severe diarrhoea could cause irritation of the rectal mucosa