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Dimethyl fumarate (DMF), an FDA-approved drug prescribed for the treatment of multiple sclerosis ( Figure 7A ), allowing NRF2 to translocate to the nucleus and become transcriptionally active ( Figure 7 Indeed, our intracellular GSH detection assay revealed that both treatment with DMF and melatonin induced increases in ILC2 GSH levels ( Figure 7B )

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Besides, the daily regular administration of exenatide without dose interruptions enabled us to achieve success in suppressing the immediate hypersensitivity reaction with a single desensitization period