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Mater Today Bio 32:101794
Alanine substitutions in Y186 1.47b and K231 2.67b had a moderate effect (416 fold) on GLP-2 potency (Fig
These events can further affect nutrient absorption and gut motility, and become a vicious cycle causing symptoms such as constipation and muscle weakness, as well as neurological issues such as mood swings, fatigue , brain fog , etc
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