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Food & Drug Administration (FDA) required a safety label for Ozempic (semaglutide) warning of the potential risk of ileus, a condition characterized by impaired intestinal motility

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The SLIMMER Phase 3 trial positioned ecnoglutide as a competitive GLP-1 agonist, with 15.4% weight loss at 48 weeks that approaches semaglutide's established efficacy, though the comparison is limited by differences in trial populations and duration