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This encompasses not only individuals dealing with conditions like menopause or hypogonadism but also transgender and non-binary people who may use HRT as part of their gender affirmation process
Other serious side effects include increased blood pressure and heart rate and, less commonly, liver damage or hepatitis, vision problems, increased risk of low blood sugar in people with type 2 diabetes, or manic episodes
However, in the SURMOUNT-4 clinical trial, participants who stopped taking tirzepatide regained some of the weight they had lost