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Given its potential influence on the ghrelin receptors, Ipamoreline might also potentially enhance appetite and, perhaps, lead to weight gain

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In those that stop taking the medications, rebound weight gain is very common

Glucagon-like peptide-1 (GLP-1) is a hormone produced by the small intestine, which is responsible for triggering the pancreas to release insulin, blocking the secretion of another hormone called glucagon, slowing digestion, and making you feel full after eating