and P.A.S.-M
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En cultivos de adipocitos, la inhibicin de NNMT con este compuesto se ha asociado con incremento de NAD+ intracelular, activacin de AMPK y aumento de la beta-oxidacin de lpidos, reduciendo el tamao de las gotas lipdicas en modelos celulares
FG-4592, a novel oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), maintains hemoglobin levels and lowers cholesterol in hemodialysis (HD) patients: phase 2 comparison with epoetin alfa [abstract]