References Lancet Diabetes Endocrinology (2024) Efficacy and safety of coadministered onceweekly cagrilintide 2.4 mg with Semaglutide 2.4 mg in type 2 diabetes: phase 2 trial Lancet (2021) Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant cagrilintide with Semaglutide 2.4 mg: phase 1b trial Lancet (2021) Onceweekly cagrilintide for weight management: dosefinding phase 2 trial in overweight/obesity StatPearls (2025) Semaglutide: pharmacology, indications, and clinical use overview Cureus (2024) Semaglutide: risks and benefits review (PMC) WHO (2010) Best practices for injection and related procedures (WHO toolkit) SigmaAldrich (2016) Peptide Handling Guide: storage, reconstitution, and stability LibreTexts (2020) Intradermal and subcutaneous injections: clinical procedures CDC (2024) Vaccine administration: subcutaneous injection technique Additional Research and Background These sources provide related context and are not presented as support for a specific statement above

We thank James O'Callaghan, PhD and Farshid Sepehrband, PhD for their support on the submitted feature image
Available at Telesford I, Schwartz H, Claxton G, et al
doi: 10.1007/s00394-020-02284-3 23 ZhaoCBaoLZhaoYWuKQiuMFengLet al
The RNA-seq and qRT-PCR results for both up- and downregulated genes showed a strong positive association (r = 0.854, p = 0.007