The Journal of Clinical Endocrinology & Metabolism, 78(3), 693698
Muscle loss is related to the process of losing weight. Rapid and significant weight loss can lead to sarcopenia (a loss of muscle mass, strength and function), especially if you arent focused on diet and exercise
This includes: Nutrition guidance A dose-escalation schedule to minimize side effects Lifestyle recommendations, including activity and behavior strategies Step 5: Ongoing Monitoring Regular follow-ups allow your provider to adjust dosing, track progress, and manage any side effects
PMC PMC8813037 Dattilo M, et al
The evidence base is almost entirely preclinical: rodent models consistently show accelerated tissue repair, gut healing, and neurological protection, but human RCT data remains largely absent