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Despite these advancements, AI-driven metabolomics models still face challenges in reproducibility and interpretability

Development of drugs characterized by biased activation may enable selective therapy and reduce adverse effects

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These findings have sparked intense scientific interest in understanding the mechanics underpinning these observations, with most studies aiming to establish where these drugs act primarily on the brain's reward centers, like addiction medications like naltrexone, or if they work through a more physical, peripheral mechanism in the body