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This damage reduces the livers ability to store and release vitamin B12 when the body needs it

In the pivotal STEP 1 clinical trial, participants who received weekly semaglutide injections lost an average of 14.9% of their body weight over 68 weeks , compared with 2.4% in the placebo group (study in the New England Journal of Medicine )

This prescription form of B12 is the one most often recommended by healthcare professionals, including primary healthcare services, because it stays in the body for longer, only requiring repeat injection every three months

This often translates to a reduced appetite and difficulty eating enough to gain weight