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Digestion-based DNA methylation analysis Percentage DNA methylation was assessed at CpG sites across CpG islands in CYP2R1, CYP27A1, CYP27B1, CYP24A1, and VDR genes using Qiagen EpiTect II methylation enzyme kits and PCR assays at the concentrations and cycle conditions recommended by the manufacturer

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Flavonoids such as quercetin and naringenin have significant ROS scavenging abilities, which help protect neuronal cells from oxidative damage ( 4.3 Inhibition of inflammation Natural products often possess anti-inflammatory properties that complement their antioxidant effects