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For observational studies (cohort and case-control), the NewcastleOttawa Scale (NOS) (La Torre et al., 2014), was applied

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Phosphatidylinositol 4-kinases, PI4K The PI4K enzymes phosphorylate phosphatidylinositol (PtdIns) on the 4-OH of the inositol to generate phosphatidylinositol-4-phosphate (PtdIns-4-P)

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