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And if food brings you no joy to eat, its all too easy to skip out altogether and put yourself in too deep of a caloric deficit

It can begin within days of the first injection, though it is often subtle at starting doses

Each patient also provided results of relevant laboratory testing and completed three standardized online questionnaires to obtain information about nutrition, dietary supplementation, and exercise practices during their obesity treatment

Setting realistic expectations is crucial: weight loss is gradual, with clinical trials showing approximately 15% weight reduction with semaglutide 2.4 mg at 68 weeks and up to 21% with tirzepatide at 72 weeks, though individual responses vary considerably