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The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

Li M, van Esch BCAM, Wagenaar GTM, Garssen J, Folkerts G, Henricks PAJ

Granger, C

Taking into account that reactive astrocytes may produce various neurotrophic factors and antioxidant molecules targeting neuronal survival, it is possible that genetic manipulation of these functions in astrocytes may represent a promising strategy to improve dopaminergic neurons or neural progenitor cells survival [4,23]

In addition to these sources, inflammatory processes in the body are significant contributors to free radical production [8]