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In erythroleukemia K562 cells, in addition to the above identified NRF2 binding ARE motif, there is also a strong association of active histone codes (such as H3K4Me3, H3K9Ac, H3K27Ac, H3K79Me2) upstream of the transcription start site (Supplementary Fig

Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway

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Semaglutide remains the option when gastrointestinal tolerance is problematic (milder profile) or on tight budget (older molecule, available in more economical formats)

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