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Both support once-weekly dosing, and a longer half-life says nothing about efficacy or safety on its own

So, even though it had never been done before, we tried it

Autopsies of patients with ASD have revealed significant structural changes in their brains, including altered grey/white matter ratios, increased neuronal numbers, decreased neuronal body volume, increased numbers of glia, and changes in dendritic spines and cerebral blood vessels