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They also note that a 5% to 10% reduction in body weight can result in improvement in clinically relevant parameters such as blood pressure, glycemic control in diabetes, lipids, and symptoms of osteoarthritis

Why constipation becomes so common on GLP-1s GLP-1 receptor agonists slow everything down

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Animal studies have shown a risk of birth defects, so use during pregnancy should be carefully considered

Researchers started describing it as a genome reset, because the pattern in aged cells shifted back toward what youd expect from younger tissue (PMID: 25815981)