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Not much is known about their side effects in older people

For breakthrough headaches, acetaminophen (Tylenol) is generally well-tolerated with GLP-1 medications

Intravenous glutathione studies report headache, dizziness, and localized injection reactions in fewer than 3% of cases

Semaglutide and Thyroid Cancer Concerns Mechanistic Theories of C-Cell Activation Animal data suggest GLP-1 receptor activation may stimulate rodent C-cell proliferation, but human thyroid C-cells express minimal GLP-1 receptors

Goosey JD, Tuan WM, Garcia CH1984A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit