thus, butyrate can decrease the cellular level of HO, which is a major indicator associated with ferroptosis (Hua et al., 2024)
The study protocol was approved by the Institutional Ethics Committee for Biomedical and Healthcare Research
Always consult with a qualified medical professional to develop a safe and effective treatment plan
Additionally, akin to the response to increased energy intake, nutrient deprivation has been shown as a potent inducer of p53 signalling in various cell types by upstream cues like AMPK signalling, fatty acids, or DNA damage 24,25,26,27
This study provides evidence that exposure of isolated fresh erythrocytes for 24 h to CSE induces eryptosis by p38 MAPK-initiated DISC formation, followed by activation of caspase-8/caspase-3 via ceramide formation by neutral SMase