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Common gastrointestinal adverse effects reported in clinical trials with Wegovy include: Nausea (affecting up to 44% of patients, particularly during dose escalation) Vomiting (reported in approximately 24% of users) Diarrhoea (occurring in around 30% of patients) Constipation (affecting approximately 24% of individuals) Abdominal pain and dyspepsia (indigestion) These effects are typically most pronounced when initiating treatment or increasing the dose, and often diminish over time as the body adjusts to the medication