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But there are a lot of unknowns. If these drugs do get approved for MASH, which Sanyal anticipates could happen before the end of the year, Su wonders how long patients would need to be treated
Goop this is not, at least not in its aesthetic, though a comparison is apt
In response to LPS, Kupffer cells, which are resident liver macrophages, and hepatic stellate cells are activated and release pro-inflammatory cytokines, this further elevates insulin resistance and promotes hepatic inflammation and fibrosis, thus having a central role in MASLD progression (137139)
MASH used to be called nonalcoholic steatohepatitis , and it is a subtype of metabolic dysfunctionassociated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease
10.2174/13816128113190990411 126 SikiricP.SeiwerthS.RucmanR.TurkovicB.RokotovD
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