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The ability of the lung to utilize GSH from the plasma seems evident based on the fact that during the rest period the plasma GSH spikes at 4 hours while at the same time point the lung GSH is slightly higher and the ELF GSH is still rising

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And in animal experiments, what theyve done is theyve said, Okay, lets give these animals inhibitors of their mitochondria at specific locations and see what methylene blue does. And if you dont have any inhibitors, and if the animal is genetically healthy, then you add methylene blue, they get less ATP, so the mitochondria is less effective at converting food to usable energy