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When its not excreted properly or not enough of it is flushed out of the body, it would result in crystals forming in different parts of the body like the big toe (gout), in the kidneys themselves (kidney stones), coronary arteries, or even in the prostate gland

In Proceedings of XI International Congress for Tropical Medicine and Malaria (1984)

doi: 10.1002/cphy.c170046 38

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The gustatory signaling pathway and bitter taste receptors affect the development of oobesity and adipocyte metabolism in mice