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Butyrate is a source of energy for intestinal epithelial cells and is required to keep the intestinal epithelial barrier from becoming vulnerable to infections

This effect is achieved through the activation of the PPAR/--catenin-TCF-4 signaling pathway within intestinal L cells, suggesting its potential in T2DM management

It can also prevent blood sugar spikes and improve cholesterol levels

Activating both GIP and GLP-1 receptors could be beneficial for DM2 treatment, as their joint actions can amplify insulin production, reduce energy usage, and enhance insulin sensitivity

Multiple ascending dose design (0.5 6 mg/week)