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doi: 10.1039/D3DT04216B 87 WangY.LiuC.RenY.SongJ.FanK.GaoL.et al

Under stress, MOTS-C translocates to the nucleus for direct gene regulation a dual-compartment mechanism unique among metabolic peptides

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In vitro studies using adipocyte precursor cell lines have investigated how this fragment influences adipogenic transcription factor expression, including PPAR and C/EBP, which are key regulators of the adipocyte differentiation programme