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Most large trials didnt exclude people with RA, but they also didnt report on them specifically, Dr

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The pathological hallmark of MS is the occurrence of focal demyelinated lesions (or plaques) disseminated throughout the CNS, causing diverse functional deficits according to their location

The GLP-1 receptor is expressed in all these subcortical target regions and also in cortical and hippocampal regions that do not get axonal input from the GLP-1 neurons in the hindbrain (Randolph et al., 2024)

Seek medical attention immediately if symptoms are severe or sudden