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Therefore, in peri- and post-menopausal patients, rapid or substantial weight loss while on semaglutide may plausibly unmask or intensify GSM symptoms via endocrine and tissue-level changesalthough the specific contribution of semaglutide vs weight loss per se is not established

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Researchers interested in GLP-1-based therapies may be familiar with liraglutide, classed along with semaglutide as a long-acting GLP-1RA hypoglycemic agent and approved for the treatment of type 2 diabetes and chronic weight management [17]