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This shift in pricing power, coupled with the IRAs differential treatment of biologics and small molecule drugs, could influence future R&D investments and potentially create challenges for companies seeking to bring new therapies to market

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Subsequently, the insulin signaling pathway was investigated in the liver by examining phosphorylation of insulin receptor substrate 1 (pIRS1)-Ser307 and phosphorylation of protein kinase B (pAKT)-Ser473