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Studies in animal models show consistent effects on gut wall integrity, including reduction of intestinal permeability markers associated with leaky gut

Study Design and Recruitment This study was an open-label prospective clinical trial conducted from April 2021 to April 2023

doi: 10.3389/fnins.2023.1225875 Summary Keywords aging, atherosclerosis, inflammaging, insulin resistance, sarcopenia Citation Yu M, Ge L, Fu C and Zhao R (2026) Unraveling the metabolic pathways between atherosclerosis and sarcopenia

A study involving a 2-hour swimming protocol in rats revealed that whey HP ingestion induced significantly higher MPS compared to the intact whey protein [189]

And the combination can lead to dehydration and electrolyte imbalances if vomiting or diarrhea becomes persistent, which creates secondary risks for kidney function and overall metabolic stability