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Long-term opioid use, including methadone maintenance therapy (MMT), can have significant side effects, including dependence, cognitive impairment, and others
The findings demonstrated that Streptozotocin-induced diabetes was associated with marked metabolic disturbances and cognitive impairment, whereas Retatrutide treatment was associated with a partial attenuation of these alterations rather than complete normalisation (present study)
Finerenone is the most recently PBS approved therapy for DKD that reduces progression of CKD and cardiovascular events
Toxins like MPP+ and rotenone, which inhibit Complex I, cause a buildup of ROS, reinforcing the connection between ETC dysfunction and disease progression in PD
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