Risk of Overdose (Rare) While Vitamin B12 is water-soluble and excess amounts are usually excreted through urine, theres still a small risk of overdose if administered too frequently
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This uptake depends on a protein called intrinsic factor (IF), which captures B12 in the small intestine, absorbing it in the final stretch of your small intestine (the ileum)
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Due to the unique characteristics of the studied population - individuals infected before completing vaccination and prior to the Omicron variants - it is not feasible to increase the sample size