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Avoid binge drinking, defined by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) as consuming 4 or more drinks for women or 5 or more drinks for men on a single occasion

A decrease in creatinine is not a conventional signal of renal injury the authors interpreted it in the context of the compounds putative protective activity rather than as toxicity but it is exactly the kind of dose-dependent biochemical change that a complete package would follow up with histopathology and mechanistic work

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doi: 10.3389/fphys.2015.00194

Using magnetically responsive particles to capture target proteins, this method streamlines workflows, improves reproducibility, and can be scaled from individual samples to high-throughput formats when integrated with automated platforms