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2026 25 Jun

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Additionally, in young overweight patients with IR and PCOS, a 12-month regimen of metformin therapy demonstrated a significant reduction in the prevalence of MS and amelioration of liver complications, enhancing insulin sensitivity ( Therefore, metformin has demonstrated efficacy in the management of PCOS in conjunction with MASLD, particularly in overweight and obese females with PCOS and IR

If substantially longer-term storage is required, unopened lyophilized vials may also be kept frozen

[1] In the first step of this pathway, H 2 O 2 is reduced to water by ascorbate peroxidase (APX) using ascorbate (ASC) as the electron donor